SLU-PP-332

SLU-PP-332 (also referenced as SLU PP332 or Sloop PP332 in some research contexts) is a synthetic small-molecule pan-agonist of the estrogen-related receptors (ERRα, ERRβ, and ERRγ). It demonstrates high binding affinity across ERR isoforms (EC50 ≈98 nM for ERRα, 230 nM for ERRβ, 430 nM for ERRγ), serving as a key investigational tool for studying ERR-mediated metabolic pathways. Extensively examined in preclinical models, SLU-PP-332 activates mitochondrial biogenesis, boosts fatty acid oxidation, elevates energy expenditure, and induces exercise-mimetic adaptations in skeletal muscle and other tissues without relying on traditional AMPK or PPARδ mechanisms.

Benefits:

• Activates mitochondrial biogenesis and cellular respiration via ERR pathway modulation
• Enhances fatty acid oxidation and metabolic efficiency in experimental models
• Supports studies on endurance, energy homeostasis, and exercise-like metabolic reprogramming

Disclaimer: This product is intended for research purposes only and is not approved for human or veterinary use.