PT-141 10mg

PT-141 (Bremelanotide) is a high-purity synthetic cyclic heptapeptide (>99% purity verified by HPLC and Mass Spectrometry) supplied by Peptide Source exclusively for in-vitro laboratory research, scientific experimentation, and academic purposes. It is a melanocortin receptor agonist (primarily targeting MC3R and MC4R) derived as an analog of α-melanocyte-stimulating hormone (α-MSH), with modifications for enhanced stability and central nervous system activity in experimental models.

Chemical and Structural Specifications:

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH (cyclic lactam bridge; Nle = norleucine, D-Phe = D-phenylalanine)
• Molecular Formula: C₅₀H₆₈N₁₄O₁₀
• Molecular Weight: 1025.2 g/mol
• CAS Number: 189691-06-3
• Form: Lyophilized (freeze-dried) white to off-white powder
• Purity: >99% (analytical grade)
• Storage Recommendation: -20°C or lower, protected from light and moisture
• Solubility: Soluble in sterile water or appropriate buffers for in-vitro use

PT-141 features key modifications from α-MSH: N-terminal acetylation with norleucine, D-phenylalanine substitution at position 7, and cyclization between Asp and Lys residues, resulting in a stable heptapeptide structure. In controlled preclinical and in-vitro research, it is utilized to investigate melanocortin receptor signaling pathways, including G-protein-coupled activation, intracellular cAMP elevation, and downstream effects on neuroendocrine circuits in cell-based assays or receptor pharmacology models. Researchers employ PT-141 as a tool to explore central melanocortin system dynamics, ligand-receptor interactions, and related biochemical mechanisms in non-human experimental systems.

Unlike full melanocortin peptides that induce peripheral effects (e.g., tanning), PT-141's modifications favor central activity, making it valuable for studies on CNS receptor pharmacology and peptide analog stability.

Critical Compliance and Safety Notice: Peptide Source supplies PT-141 strictly for research laboratory use only (in-vitro experiments, receptor binding assays, cell culture studies, signaling pathway analysis, etc.). This product is not intended, approved, or safe for human use, consumption, self-administration, arousal enhancement, sexual function studies in humans, therapeutic purposes, or any non-research application. It is not for food, drug, cosmetic, or veterinary use. Researchers must adhere to institutional biosafety protocols, safety guidelines, and local regulations. Peptide Source provides no medical advice and prohibits any misuse. Certificates of Analysis (COA) are available upon request to verify purity, identity, and quality.

Peptide Source is a trusted supplier of premium research peptides like PT-141 10mg (Bremelanotide), with rigorous quality control, secure packaging, and fast worldwide shipping (including Greece). Contact us for bulk options or documentation.