Melanotan II

Melanotan 2 (MT-II, Melanotan II) is a high-purity synthetic cyclic heptapeptide (>99% purity confirmed by HPLC and Mass Spectrometry) supplied by Peptide Source strictly for in-vitro laboratory research, scientific experimentation, and academic purposes. This peptide is a potent, non-selective agonist of melanocortin receptors (MC1R, MC3R, MC4R, MC5R), designed as an analog of α-melanocyte-stimulating hormone (α-MSH).

Chemical and Structural Specifications:

• Sequence: Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ (cyclic lactam bridge between Asp and Lys)
• Molecular Formula: C₅₀H₆₉N₁₅O₉
• Molecular Weight: 1024.18–1024.2 g/mol
• CAS Number: 121062-08-6
• Form: Lyophilized (freeze-dried) white powder for enhanced stability
• Purity: >99% (analytical grade, verified)
• Storage Recommendation: -20°C or below, protected from light and moisture; avoid repeated freeze-thaw cycles
• Solubility: Soluble in sterile water or suitable buffers for in-vitro applications

Melanotan 2 is a modified version of α-MSH with an N-terminal acetyl-norleucine substitution and a D-phenylalanine at position 7, resulting in increased stability, potency, and receptor affinity compared to the endogenous hormone. In controlled research settings, it is utilized to investigate melanocortin receptor signaling pathways, including cAMP activation, G-protein-coupled receptor (GPCR) dynamics, pigmentation mechanisms in melanocyte models, and broader neuroendocrine/physiological responses in non-human experimental systems.

This cyclic structure contributes to prolonged activity in peptide-receptor interaction studies, making Melanotan 2 a valuable reagent for exploring melanogenesis-related biochemistry, receptor binding assays, and signal transduction in cell culture or preclinical models.

Critical Compliance and Safety Notice: Peptide Source supplies Melanotan 2 exclusively for research laboratory use (in-vitro, cell-based assays, receptor pharmacology, etc.). This product is not intended, approved, or safe for human use, consumption, self-administration, tanning, therapeutic purposes, diagnosis, or any non-research application. It is not for food, drug, cosmetic, or veterinary use. Researchers must handle it according to institutional safety protocols, biosafety guidelines, and local regulations. Peptide Source provides no medical advice and prohibits any misuse. Certificates of Analysis (COA) are available upon request to confirm identity, purity, and quality.

Peptide Source is your reliable supplier of premium research peptides like Melanotan 2 10mg, with rigorous quality control, secure packaging, and fast worldwide shipping (including Greece). Contact us for bulk options or additional documentation.