Trezepitide 60mg

Tirzepatide is a high-purity synthetic 39-amino acid linear polypeptide (>99% purity verified by HPLC and Mass Spectrometry) supplied by Peptide Source exclusively for in-vitro laboratory research, scientific experimentation, and academic purposes. It functions as a dual agonist of glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor, modified for enhanced stability and pharmacokinetics in controlled research settings.

Chemical and Structural Specifications:

• Sequence: Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{C20 diacid-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH₂ (Aib = 2-aminoisobutyric acid; lipidated at Lys20 via gamma-Glu and AEEA linkers to C20 fatty diacid)
• Molecular Formula: C₂₂₅H₃₄₈N₄₈O₆₈
• Molecular Weight: 4813.45–4813.53 g/mol
• CAS Number: 2023788-19-2
• Form: Lyophilized (freeze-dried) white powder for stability
• Purity: >99% (analytical grade)
• Storage Recommendation: -20°C or lower, protected from light and moisture
• Solubility: Soluble in sterile water or appropriate buffers for in vitro use

Tirzepatide is based on the native GIP sequence with key modifications: substitution of glycine with 2-aminoisobutyric acid (Aib) at positions 2 and 13 for resistance to DPP-4 degradation, and conjugation of a C20 fatty diacid moiety at lysine-20 via a linker (gamma-Glu-(AEEA)₂) to promote albumin binding and extend half-life in experimental models. In preclinical and in vitro research, it is used to study dual incretin receptor signaling, including cAMP elevation, modulation of insulin secretion in beta-cell models, glucagon dynamics, and metabolic pathway investigations in non-human systems.

This lipidated structure enhances bioavailability and duration in research assays, making tirzepatide a valuable tool for exploring incretin mimetics, receptor pharmacology, glucose homeostasis mechanisms, and related biochemical pathways in cell culture, receptor binding, or animal model studies.

Critical Compliance and Safety Notice: Peptide Source supplies tirzepatide strictly for research laboratory use only (in-vitro experiments, cell-based assays, receptor studies, etc.). This product is not intended, approved, or safe for human use, consumption, self-administration, therapeutic purposes, diagnosis, weight management, diabetes treatment, or any non-research application. It is not for food, drug, cosmetic, or veterinary use. Researchers are responsible for proper handling, storage, and compliance with institutional biosafety protocols and regulations. Peptide Source provides no medical advice and strictly prohibits misuse. Certificates of Analysis (COA) are available upon request for purity and identity verification.

Peptide Source is a trusted supplier of premium research peptides like tirzepatide 60mg, with quality control, secure packaging, and fast worldwide shipping (including Greece). Contact us for bulk inquiries or documentation.